Saturday, 4 September 2010

Spironolactone




In some countries, this medicine may only be approved for veterinary use.


In the US, Spironolactone (spironolactone systemic) is a member of the following drug classes: aldosterone receptor antagonists, potassium-sparing diuretics and is used to treat Acne, Alopecia, Edema, Heart Failure, High Blood Pressure, Hirsutism, Hypokalemia, Primary Hyperaldosteronism and Primary Hyperaldosteronism Diagnosis.

US matches:

  • Spironolactone

  • Spironolactone and hydrochlorothiazide

  • Spironolactone/Hydrochlorothiazide

UK matches:

  • Spironolactone Tablets 25mg, 50mg, 100mg

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C03DA01

CAS registry number (Chemical Abstracts Service)

0000052-01-7

Chemical Formula

C24-H32-O4-S

Molecular Weight

416

Therapeutic Category

Potassium-sparing diuretic agent, aldosterone antagonist

Chemical Name

Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, þ-lactone, (7α,17α)-

Foreign Names

  • Spironolactonum (Latin)
  • Spironolacton (German)
  • Spironolactone (French)
  • Espironolactona (Spanish)

Generic Names

  • Spironolactone (OS: BAN, DCF, JAN)
  • Spironolattone (OS: DCIT)
  • SC 9420 (IS)
  • Spironolacton (PH: Ph. Eur. 6)
  • Spironolactone (PH: BP 2010, JP XIV, Ph. Int. 4, USP 32, Ph. Eur. 6)
  • Spironolactonum (PH: Ph. Int. 4, Ph. Eur. 6)

Brand Names

  • Aldactacine (Spironolactone and Altizide)
    Pfizer, Spain


  • Aldactazide (Spironolactone and Hydrochlorothiazide)
    Pfizer, Canada; Pfizer, United States; SPA, Italy


  • Aldactazine (Spironolactone and Altizide)
    Continental, Belgium; Continental, Luxembourg; Pfizer, France; Pfizer, Tunisia


  • Aldactide (Spironolactone and Hydroflumethiazide)
    Pfizer, Bahrain; Pfizer, United Kingdom; Pharmacia, Ireland


  • Aldactone
    ARIS, Turkey; Cheplapharm, Austria; Continental, Belgium; Continental, Luxembourg; Grünenthal, Colombia; Lepetit, Italy; Pfizer, United Arab Emirates; Pfizer, Argentina; Pfizer, Australia; Pfizer, Burkina Faso; Pfizer, Bahrain; Pfizer, Benin; Pfizer, Brazil; Pfizer, Canada; Pfizer, Central African Republic; Pfizer, Congo; Pfizer, Switzerland; Pfizer, Cote D'ivoire; Pfizer, Cameroon; Pfizer, Costa Rica; Pfizer, Cyprus; Pfizer, Ecuador; Pfizer, Egypt; Pfizer, Spain; Pfizer, France; Pfizer, Gabon; Pfizer, United Kingdom; Pfizer, Ghana; Pfizer, Guinea; Pfizer, Greece; Pfizer, Guatemala; Pfizer, Hong Kong; Pfizer, Honduras; Pfizer, Ireland; Pfizer, Israel; Pfizer, Iceland; Pfizer, Jordan; Pfizer, Kenya; Pfizer, Lebanon; Pfizer, Madagascar; Pfizer, Mali; Pfizer, Myanmar; Pfizer, Mauritania; Pfizer, Malta; Pfizer, Mauritius; Pfizer, Mexico; Pfizer, Niger; Pfizer, Nigeria; Pfizer, Norway; Pfizer, Oman; Pfizer, Panama; Pfizer, Philippines; Pfizer, Portugal; Pfizer, Saudi Arabia; Pfizer, Sweden; Pfizer, Singapore; Pfizer, Senegal; Pfizer, El Salvador; Pfizer, Chad; Pfizer, Togo; Pfizer, Thailand; Pfizer, Tunisia; Pfizer, United States; Pfizer, Venezuela; Pfizer, South Africa; Pfizer, Zaire; Pfizer Pharma, Ethiopia; Riemser, Germany; Riemser, Croatia (Hrvatska); Riemser, Slovenia; RPG, India; Soho, Indonesia


  • Aldactone (veterinary use)
    Pfizer Animal Health, United Kingdom


  • Aldactone-A
    ARIS, Turkey; Pfizer, Argentina; Pfizer, Spain; Pfizer, Guyana; Pfizer, Japan; Pfizer, Peru


  • Aldactone-Saltucin forte (Spironolactone and Butizide)
    Cheplapharm, Austria


  • Aldalix (Spironolactone and Furosemide)
    Pfizer, France; Pfizer, Tunisia


  • Aldazide (Spironolactone and Butizide)
    Pfizer, South Africa; Soho, Indonesia


  • Aldoleo (Spironolactone and Chlortalidone)
    Nycomed, Spain


  • Aldonar
    Upsifarma, Portugal


  • Aldospirone
    Teva, Israel


  • Aldozone (Spironolactone and Butizide)
    Pfizer, Switzerland


  • Alexan
    Sanwa Kagaku, Japan


  • Alizar
    Gynopharm, Chile


  • Almatol
    Choseido Pharmaceutical, Japan


  • Alspiron
    Helcor, Romania


  • Aporasnon
    Nichi-Iko PharmaceuticalJMA, Japan


  • Cardactona
    Pasteur, Chile


  • Cardiatone
    Dr. Collado, Dominican Republic


  • Carpiaton
    Fahrenheit, Indonesia


  • Diulactone
    Searle, Vietnam


  • Doc Spirono
    Docpharma, Luxembourg


  • Docspirochlor (Spironolactone and Hydrochlorothiazide)
    Docpharma, Belgium


  • Docspirono
    Docpharma, Belgium; Docpharma, Luxembourg


  • Espimax
    Klonal, Argentina


  • Espirone
    Carrion, Peru


  • Espironolactona AC Farma
    AC Farma, Peru


  • Espironolactona Alter
    Alter, Spain; Alter, Portugal


  • Espironolactona Denver
    Denver, Argentina


  • Espironolactona Farmindustria
    Farmindustria, Peru


  • Espironolactona Generis
    Generis, Portugal


  • Espironolactona L.CH.
    Chile, Chile


  • Espironolactona Northia
    Northia, Argentina


  • Espironolactona
    Bestpharma, Chile; Blaskov, Colombia; Ecuaquímica, Ecuador; Meyer, Venezuela; Mintlab, Chile


  • Expal
    Bagó, Argentina


  • Furo Aldopur (Spironolactone and Furosemide)
    Kwizda, Germany


  • Furorese comp (Spironolactone and Furosemide)
    Hexal, Germany


  • Furospir (Spironolactone and Furosemide)
    Mepha Pharma, Switzerland


  • Furo-Spirobene (Spironolactone and Furosemide)
    Ratiopharm, Austria


  • Hexalacton
    Sandoz, Denmark


  • Huma-Spiroton
    Teva, Hungary


  • Jenaspiron
    Mibe Jena, Germany


  • Kespirona
    Heimdall, Colombia


  • Lacalmin
    Tatsumi Kagaku, Japan


  • Lanx
    Elea, Argentina


  • Lasilacton (Spironolactone and Furosemide)
    Sanofi-Aventis, Austria; Sanofi-Aventis, Switzerland


  • Lasilactone (Spironolactone and Furosemide)
    Sanofi-Aventis, United Kingdom


  • Lasitone (Spironolactone and Furosemide)
    Sanofi-Aventis, Italy


  • Letonal
    Otto, Indonesia


  • Macacy
    A Nipro PharmaNipurofama, Japan


  • Merlactone
    Kobayashi Kako, Japan


  • Modulactone
    Lafedar, Argentina


  • Nefrotone
    Socobom, Luxembourg


  • Noidouble
    Kyorin Rimedio, Japan


  • Noractone
    Saiph, Tunisia


  • Normital
    Phoenix, Argentina


  • Novo-Spiroton
    Novopharm, Canada


  • Novo-Spirozine (Spironolactone and Hydrochlorothiazide)
    Novopharm, Canada


  • Osiren
    Lafedar, Argentina


  • Osyrol
    Sanofi-Aventis, Germany


  • Osyrol Lasix (Spironolactone and Furosemide)
    Sanofi-Aventis, Germany


  • Pilactone
    Sanofi-Aventis, Bangladesh


  • Pirolacton
    Taiyo Pharmaceutical, Japan


  • Practazin (Spironolactone and Altizide)
    Pfizer, France


  • Practon
    Pfizer, France


  • Prilactone (veterinary use)
    Ceva, Austria; Ceva, Belgium; Ceva, Germany; Ceva, France


  • Rakudeen
    Tsuruhara Seiyaku, Japan


  • Rediun-E
    Baliarda, Argentina


  • Sali-Aldopur (Spironolactone and Bendroflumethiazid)
    Wabosan, Austria


  • Sandoz Spironolactone
    Sandoz, South Africa


  • Spilactone
    Sankei Yakuhin, Japan


  • Spiractin
    Alphapharm, Australia; Aspen Pharmacare, South Africa


  • Spiresis
    Orion, Finland


  • Spirix
    Leiras, Finland; Nycomed, Denmark; Nycomed, Estonia; Nycomed, Iceland; Nycomed, Lithuania; Nycomed, Latvia; Nycomed, Norway


  • Spiro comp.-ratiopharm (Spironolactone and Furosemide)
    Ratiopharm, Germany


  • Spirobene
    Ratiopharm, Austria


  • Spirobeta
    Betapharm, Germany


  • Spiro-CT
    CT Arzneimittel, Germany


  • Spiroctan
    Ferlux, France


  • Spiroctazide (Spironolactone and Altizide)
    Ferlux, France


  • Spiro-D-Tablinen (Spironolactone and Furosemide)
    Winthrop, Germany


  • Spirogamma
    Wörwag Pharma, Germany; Wörwag Pharma, Estonia; Wörwag Pharma, Latvia; Wörwag Pharma, Poland


  • Spirohexal
    Hexal, Austria


  • Spirola
    Kalbe, Indonesia


  • Spirolacton
    Phapros Tbk, Indonesia


  • Spirolang
    SIT, Italy


  • Spirolon
    Remedica, Cyprus; Remedica, Kenya; Remedica, Sudan; Remedica, Zimbabwe


  • Spiromide (Spironolactone and Furosemide)
    Pfizer, Myanmar; Searle, Vietnam


  • Spiron
    Orion, Denmark; ratiopharm, Hungary


  • Spirono Genericon comp. (Spironolactone and Furosemide)
    Genericon, Austria


  • Spirono Genericon
    Genericon, Austria


  • Spirono-Isis
    Actavis, Germany


  • Spironol
    Pharmachemie, Israel; Polfa Grodzisk, Poland


  • Spironolacton A
    Apothecon, Netherlands


  • Spironolacton AAA
    AAA-Pharma, Germany


  • Spironolacton AccordHealthcare
    Accord Healthcare, Netherlands


  • Spironolacton Actavis
    Balkanpharma, Bulgaria


  • Spironolacton Agepha
    Agepha, Austria


  • Spironolacton AL
    Aliud, Germany


  • Spironolacton Aristo
    Aristo Pharma, Germany


  • Spironolacton AWD
    AWD.pharma, Germany


  • Spironolacton CF
    Centrafarm, Netherlands


  • Spironolacton dura
    Mylan dura, Germany


  • Spironolacton Heumann
    Heumann, Germany


  • Spironolacton Hexal
    Hexal, Germany


  • Spironolacton Katwijk
    Apotex Europe, Netherlands


  • Spironolacton Lindopharm
    Lindopharm, Germany


  • Spironolacton Merck
    Mylan, Netherlands


  • Spironolacton PCH
    Pharmachemie, Netherlands


  • Spironolacton Sandoz
    Sandoz, Germany; Sandoz, Netherlands


  • Spironolacton Stada
    Stada, Germany


  • Spironolacton TAD
    TAD, Germany


  • Spironolacton Tchaikapharma
    Tchaikapharma, Bulgaria


  • Spironolacton
    Actavis, Georgia; GenRx, Netherlands; Wise, Netherlands


  • Spironolactonã
    Bio EEL, Romania; Laropharm, Romania; Ozone Laboratories, Romania; Terapia, Romania


  • Spironolactone Altizide Arrow (Spironolactone and Altizide)
    Arrow, France


  • Spironolactone Altizide Biogaran (Spironolactone and Altizide)
    Biogaran, France


  • Spironolactone Altizide EG (Spironolactone and Altizide)
    EG Labo, France


  • Spironolactone Altizide Merck (Spironolactone and Altizide)
    Mylan, France


  • Spironolactone Altizide RPG (Spironolactone and Altizide)
    RPG, France


  • Spironolactone Altizide Sandoz (Spironolactone and Altizide)
    Sandoz, France


  • Spironolactone Altizide Teva (Spironolactone and Altizide)
    Teva Santé, France


  • Spironolactone Altizide Winthrop (Spironolactone and Altizide)
    Sanofi-Aventis, France


  • Spironolactone and Hydrochlorothiazide (Spironolactone and Hydrochlorothiazide)
    Mutual, United States; Mylan, United States; Sandoz, United States; United Pharmaceuticals, United States; URL, United States; Watson, United States


  • Spironolactone and Hydrochlorothiazide (Spironolactone and Spironolactone)
    Sandoz, United States


  • Spironolactone Apotex
    Apotex, Belgium


  • Spironolactone Arrow
    Arrow, France


  • Spironolactone Biogaran
    Biogaran, France


  • Spironolactone EG
    EG Labo, France; Eurogenerics, Belgium


  • Spironolactone G Gam
    G Gam, France


  • Spironolactone Merck
    Mylan, France


  • Spironolactone Minsheng Pharm
    Minsheng, China


  • Spironolactone Ratiopharm
    Ratiopharm, France


  • Spironolactone RPG
    RPG, France


  • Spironolactone Sandoz
    Sandoz, Belgium; Sandoz, France


  • Spironolactone Teva
    Teva Santé, France


  • Spironolactone Winthrop
    Sanofi-Aventis, France


  • Spironolactone
    Actavis, United Kingdom; Actavis, United States; Biomed, New Zealand; Mutual, United States; Mylan, United States; Sandoz, United States; Shou Chan, Taiwan; UDL, United States; United Research, United States; URL, United States; Vintage, United States


  • Spironolactone-Eurogenerics
    Eurogenerics, Luxembourg


  • Spironolactone-Sandoz
    Sandoz, Luxembourg


  • Spironolacton-ratiopharm
    Ratiopharm, Germany; Ratiopharm, Estonia; Ratiopharm, Lithuania; Ratiopharm, Luxembourg; Ratiopharm, Netherlands


  • Spironolakton Nycomed
    Nycomed, Sweden


  • Spironolakton Pfizer
    Pfizer, Sweden


  • Spironolakton
    Galenika, Serbia


  • Spironone
    Dexo, France


  • Spironothiazid (Spironolactone and Hydrochlorothiazide)
    Desma, Germany


  • Spirotone
    Pacific, New Zealand


  • Uractone
    SPA, Italy


  • Uractonum
    Medochemie, Latvia; Medochemie, Singapore


  • Urusonin
    Isei, Japan


  • Velactone
    Vee Excel, Myanmar


  • Verospilactone
    Obolenskoe, Russian Federation


  • Verospiron
    Gedeon Richter, Czech Republic; Gedeon Richter, Estonia; Gedeon Richter, Ethiopia; Gedeon Richter, Georgia; Gedeon Richter, Hungary; Gedeon Richter, Lithuania; Gedeon Richter, Latvia; Gedeon Richter, Poland; Gedeon Richter, Romania; Gedeon Richter, Russian Federation; Gedeon Richter, Vietnam; Hormosan, Germany; Richter Gedeon RT, Slovakia


  • Vivitar
    Armstrong, Mexico


  • Xenalon
    Mepha Pharma, Switzerland


  • Youlactone
    Yoshindo, Japan

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.
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