In some countries, this medicine may only be approved for veterinary use.
In the US, Spironolactone (spironolactone systemic) is a member of the following drug classes: aldosterone receptor antagonists, potassium-sparing diuretics and is used to treat Acne, Alopecia, Edema, Heart Failure, High Blood Pressure, Hirsutism, Hypokalemia, Primary Hyperaldosteronism and Primary Hyperaldosteronism Diagnosis.
US matches:
- Spironolactone
- Spironolactone and hydrochlorothiazide
- Spironolactone/Hydrochlorothiazide
UK matches:
- Spironolactone Tablets 25mg, 50mg, 100mg
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
C03DA01
CAS registry number (Chemical Abstracts Service)
0000052-01-7
Chemical Formula
C24-H32-O4-S
Molecular Weight
416
Therapeutic Category
Potassium-sparing diuretic agent, aldosterone antagonist
Chemical Name
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, þ-lactone, (7α,17α)-
Foreign Names
- Spironolactonum (Latin)
- Spironolacton (German)
- Spironolactone (French)
- Espironolactona (Spanish)
Generic Names
- Spironolactone (OS: BAN, DCF, JAN)
- Spironolattone (OS: DCIT)
- SC 9420 (IS)
- Spironolacton (PH: Ph. Eur. 6)
- Spironolactone (PH: BP 2010, JP XIV, Ph. Int. 4, USP 32, Ph. Eur. 6)
- Spironolactonum (PH: Ph. Int. 4, Ph. Eur. 6)
Brand Names
- Aldactacine (Spironolactone and Altizide)
Pfizer, Spain
- Aldactazide (Spironolactone and Hydrochlorothiazide)
Pfizer, Canada; Pfizer, United States; SPA, Italy
- Aldactazine (Spironolactone and Altizide)
Continental, Belgium; Continental, Luxembourg; Pfizer, France; Pfizer, Tunisia
- Aldactide (Spironolactone and Hydroflumethiazide)
Pfizer, Bahrain; Pfizer, United Kingdom; Pharmacia, Ireland
- Aldactone
ARIS, Turkey; Cheplapharm, Austria; Continental, Belgium; Continental, Luxembourg; Grünenthal, Colombia; Lepetit, Italy; Pfizer, United Arab Emirates; Pfizer, Argentina; Pfizer, Australia; Pfizer, Burkina Faso; Pfizer, Bahrain; Pfizer, Benin; Pfizer, Brazil; Pfizer, Canada; Pfizer, Central African Republic; Pfizer, Congo; Pfizer, Switzerland; Pfizer, Cote D'ivoire; Pfizer, Cameroon; Pfizer, Costa Rica; Pfizer, Cyprus; Pfizer, Ecuador; Pfizer, Egypt; Pfizer, Spain; Pfizer, France; Pfizer, Gabon; Pfizer, United Kingdom; Pfizer, Ghana; Pfizer, Guinea; Pfizer, Greece; Pfizer, Guatemala; Pfizer, Hong Kong; Pfizer, Honduras; Pfizer, Ireland; Pfizer, Israel; Pfizer, Iceland; Pfizer, Jordan; Pfizer, Kenya; Pfizer, Lebanon; Pfizer, Madagascar; Pfizer, Mali; Pfizer, Myanmar; Pfizer, Mauritania; Pfizer, Malta; Pfizer, Mauritius; Pfizer, Mexico; Pfizer, Niger; Pfizer, Nigeria; Pfizer, Norway; Pfizer, Oman; Pfizer, Panama; Pfizer, Philippines; Pfizer, Portugal; Pfizer, Saudi Arabia; Pfizer, Sweden; Pfizer, Singapore; Pfizer, Senegal; Pfizer, El Salvador; Pfizer, Chad; Pfizer, Togo; Pfizer, Thailand; Pfizer, Tunisia; Pfizer, United States; Pfizer, Venezuela; Pfizer, South Africa; Pfizer, Zaire; Pfizer Pharma, Ethiopia; Riemser, Germany; Riemser, Croatia (Hrvatska); Riemser, Slovenia; RPG, India; Soho, Indonesia
- Aldactone (veterinary use)
Pfizer Animal Health, United Kingdom
- Aldactone-A
ARIS, Turkey; Pfizer, Argentina; Pfizer, Spain; Pfizer, Guyana; Pfizer, Japan; Pfizer, Peru
- Aldactone-Saltucin forte (Spironolactone and Butizide)
Cheplapharm, Austria
- Aldalix (Spironolactone and Furosemide)
Pfizer, France; Pfizer, Tunisia
- Aldazide (Spironolactone and Butizide)
Pfizer, South Africa; Soho, Indonesia
- Aldoleo (Spironolactone and Chlortalidone)
Nycomed, Spain
- Aldonar
Upsifarma, Portugal
- Aldospirone
Teva, Israel
- Aldozone (Spironolactone and Butizide)
Pfizer, Switzerland
- Alexan
Sanwa Kagaku, Japan
- Alizar
Gynopharm, Chile
- Almatol
Choseido Pharmaceutical, Japan
- Alspiron
Helcor, Romania
- Aporasnon
Nichi-Iko PharmaceuticalJMA, Japan
- Cardactona
Pasteur, Chile
- Cardiatone
Dr. Collado, Dominican Republic
- Carpiaton
Fahrenheit, Indonesia
- Diulactone
Searle, Vietnam
- Doc Spirono
Docpharma, Luxembourg
- Docspirochlor (Spironolactone and Hydrochlorothiazide)
Docpharma, Belgium
- Docspirono
Docpharma, Belgium; Docpharma, Luxembourg
- Espimax
Klonal, Argentina
- Espirone
Carrion, Peru
- Espironolactona AC Farma
AC Farma, Peru
- Espironolactona Alter
Alter, Spain; Alter, Portugal
- Espironolactona Denver
Denver, Argentina
- Espironolactona Farmindustria
Farmindustria, Peru
- Espironolactona Generis
Generis, Portugal
- Espironolactona L.CH.
Chile, Chile
- Espironolactona Northia
Northia, Argentina
- Espironolactona
Bestpharma, Chile; Blaskov, Colombia; Ecuaquímica, Ecuador; Meyer, Venezuela; Mintlab, Chile
- Expal
Bagó, Argentina
- Furo Aldopur (Spironolactone and Furosemide)
Kwizda, Germany
- Furorese comp (Spironolactone and Furosemide)
Hexal, Germany
- Furospir (Spironolactone and Furosemide)
Mepha Pharma, Switzerland
- Furo-Spirobene (Spironolactone and Furosemide)
Ratiopharm, Austria
- Hexalacton
Sandoz, Denmark
- Huma-Spiroton
Teva, Hungary
- Jenaspiron
Mibe Jena, Germany
- Kespirona
Heimdall, Colombia
- Lacalmin
Tatsumi Kagaku, Japan
- Lanx
Elea, Argentina
- Lasilacton (Spironolactone and Furosemide)
Sanofi-Aventis, Austria; Sanofi-Aventis, Switzerland
- Lasilactone (Spironolactone and Furosemide)
Sanofi-Aventis, United Kingdom
- Lasitone (Spironolactone and Furosemide)
Sanofi-Aventis, Italy
- Letonal
Otto, Indonesia
- Macacy
A Nipro PharmaNipurofama, Japan
- Merlactone
Kobayashi Kako, Japan
- Modulactone
Lafedar, Argentina
- Nefrotone
Socobom, Luxembourg
- Noidouble
Kyorin Rimedio, Japan
- Noractone
Saiph, Tunisia
- Normital
Phoenix, Argentina
- Novo-Spiroton
Novopharm, Canada
- Novo-Spirozine (Spironolactone and Hydrochlorothiazide)
Novopharm, Canada
- Osiren
Lafedar, Argentina
- Osyrol
Sanofi-Aventis, Germany
- Osyrol Lasix (Spironolactone and Furosemide)
Sanofi-Aventis, Germany
- Pilactone
Sanofi-Aventis, Bangladesh
- Pirolacton
Taiyo Pharmaceutical, Japan
- Practazin (Spironolactone and Altizide)
Pfizer, France
- Practon
Pfizer, France
- Prilactone (veterinary use)
Ceva, Austria; Ceva, Belgium; Ceva, Germany; Ceva, France
- Rakudeen
Tsuruhara Seiyaku, Japan
- Rediun-E
Baliarda, Argentina
- Sali-Aldopur (Spironolactone and Bendroflumethiazid)
Wabosan, Austria
- Sandoz Spironolactone
Sandoz, South Africa
- Spilactone
Sankei Yakuhin, Japan
- Spiractin
Alphapharm, Australia; Aspen Pharmacare, South Africa
- Spiresis
Orion, Finland
- Spirix
Leiras, Finland; Nycomed, Denmark; Nycomed, Estonia; Nycomed, Iceland; Nycomed, Lithuania; Nycomed, Latvia; Nycomed, Norway
- Spiro comp.-ratiopharm (Spironolactone and Furosemide)
Ratiopharm, Germany
- Spirobene
Ratiopharm, Austria
- Spirobeta
Betapharm, Germany
- Spiro-CT
CT Arzneimittel, Germany
- Spiroctan
Ferlux, France
- Spiroctazide (Spironolactone and Altizide)
Ferlux, France
- Spiro-D-Tablinen (Spironolactone and Furosemide)
Winthrop, Germany
- Spirogamma
Wörwag Pharma, Germany; Wörwag Pharma, Estonia; Wörwag Pharma, Latvia; Wörwag Pharma, Poland
- Spirohexal
Hexal, Austria
- Spirola
Kalbe, Indonesia
- Spirolacton
Phapros Tbk, Indonesia
- Spirolang
SIT, Italy
- Spirolon
Remedica, Cyprus; Remedica, Kenya; Remedica, Sudan; Remedica, Zimbabwe
- Spiromide (Spironolactone and Furosemide)
Pfizer, Myanmar; Searle, Vietnam
- Spiron
Orion, Denmark; ratiopharm, Hungary
- Spirono Genericon comp. (Spironolactone and Furosemide)
Genericon, Austria
- Spirono Genericon
Genericon, Austria
- Spirono-Isis
Actavis, Germany
- Spironol
Pharmachemie, Israel; Polfa Grodzisk, Poland
- Spironolacton A
Apothecon, Netherlands
- Spironolacton AAA
AAA-Pharma, Germany
- Spironolacton AccordHealthcare
Accord Healthcare, Netherlands
- Spironolacton Actavis
Balkanpharma, Bulgaria
- Spironolacton Agepha
Agepha, Austria
- Spironolacton AL
Aliud, Germany
- Spironolacton Aristo
Aristo Pharma, Germany
- Spironolacton AWD
AWD.pharma, Germany
- Spironolacton CF
Centrafarm, Netherlands
- Spironolacton dura
Mylan dura, Germany
- Spironolacton Heumann
Heumann, Germany
- Spironolacton Hexal
Hexal, Germany
- Spironolacton Katwijk
Apotex Europe, Netherlands
- Spironolacton Lindopharm
Lindopharm, Germany
- Spironolacton Merck
Mylan, Netherlands
- Spironolacton PCH
Pharmachemie, Netherlands
- Spironolacton Sandoz
Sandoz, Germany; Sandoz, Netherlands
- Spironolacton Stada
Stada, Germany
- Spironolacton TAD
TAD, Germany
- Spironolacton Tchaikapharma
Tchaikapharma, Bulgaria
- Spironolacton
Actavis, Georgia; GenRx, Netherlands; Wise, Netherlands
- Spironolactonã
Bio EEL, Romania; Laropharm, Romania; Ozone Laboratories, Romania; Terapia, Romania
- Spironolactone Altizide Arrow (Spironolactone and Altizide)
Arrow, France
- Spironolactone Altizide Biogaran (Spironolactone and Altizide)
Biogaran, France
- Spironolactone Altizide EG (Spironolactone and Altizide)
EG Labo, France
- Spironolactone Altizide Merck (Spironolactone and Altizide)
Mylan, France
- Spironolactone Altizide RPG (Spironolactone and Altizide)
RPG, France
- Spironolactone Altizide Sandoz (Spironolactone and Altizide)
Sandoz, France
- Spironolactone Altizide Teva (Spironolactone and Altizide)
Teva Santé, France
- Spironolactone Altizide Winthrop (Spironolactone and Altizide)
Sanofi-Aventis, France
- Spironolactone and Hydrochlorothiazide (Spironolactone and Hydrochlorothiazide)
Mutual, United States; Mylan, United States; Sandoz, United States; United Pharmaceuticals, United States; URL, United States; Watson, United States
- Spironolactone and Hydrochlorothiazide (Spironolactone and Spironolactone)
Sandoz, United States
- Spironolactone Apotex
Apotex, Belgium
- Spironolactone Arrow
Arrow, France
- Spironolactone Biogaran
Biogaran, France
- Spironolactone EG
EG Labo, France; Eurogenerics, Belgium
- Spironolactone G Gam
G Gam, France
- Spironolactone Merck
Mylan, France
- Spironolactone Minsheng Pharm
Minsheng, China
- Spironolactone Ratiopharm
Ratiopharm, France
- Spironolactone RPG
RPG, France
- Spironolactone Sandoz
Sandoz, Belgium; Sandoz, France
- Spironolactone Teva
Teva Santé, France
- Spironolactone Winthrop
Sanofi-Aventis, France
- Spironolactone
Actavis, United Kingdom; Actavis, United States; Biomed, New Zealand; Mutual, United States; Mylan, United States; Sandoz, United States; Shou Chan, Taiwan; UDL, United States; United Research, United States; URL, United States; Vintage, United States
- Spironolactone-Eurogenerics
Eurogenerics, Luxembourg
- Spironolactone-Sandoz
Sandoz, Luxembourg
- Spironolacton-ratiopharm
Ratiopharm, Germany; Ratiopharm, Estonia; Ratiopharm, Lithuania; Ratiopharm, Luxembourg; Ratiopharm, Netherlands
- Spironolakton Nycomed
Nycomed, Sweden
- Spironolakton Pfizer
Pfizer, Sweden
- Spironolakton
Galenika, Serbia
- Spironone
Dexo, France
- Spironothiazid (Spironolactone and Hydrochlorothiazide)
Desma, Germany
- Spirotone
Pacific, New Zealand
- Uractone
SPA, Italy
- Uractonum
Medochemie, Latvia; Medochemie, Singapore
- Urusonin
Isei, Japan
- Velactone
Vee Excel, Myanmar
- Verospilactone
Obolenskoe, Russian Federation
- Verospiron
Gedeon Richter, Czech Republic; Gedeon Richter, Estonia; Gedeon Richter, Ethiopia; Gedeon Richter, Georgia; Gedeon Richter, Hungary; Gedeon Richter, Lithuania; Gedeon Richter, Latvia; Gedeon Richter, Poland; Gedeon Richter, Romania; Gedeon Richter, Russian Federation; Gedeon Richter, Vietnam; Hormosan, Germany; Richter Gedeon RT, Slovakia
- Vivitar
Armstrong, Mexico
- Xenalon
Mepha Pharma, Switzerland
- Youlactone
Yoshindo, Japan
International Drug Name Search
Glossary
| BAN | British Approved Name |
| DCF | Dénomination Commune Française |
| DCIT | Denominazione Comune Italiana |
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Click for further information on drug naming conventions and
International Nonproprietary Names.
