Max HC Liquid

Pronunciation: car-bihn-OCKS-ah-meen/hye-droe-KOE-done/fen-il-EF-rin
Generic Name: Carbinoxamine/Hydrocodone/Phenylephrine
Brand Name: Examples include Excof-SF and Max HC

Max HC Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory tract infections, and allergies. It may also be used for other conditions as determined by your doctor.

Max HC Liquid is a decongestant, antihistamine, and narcotic cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Max HC Liquid if:

• you are allergic to any ingredient in Max HC Liquid or any other codeine- or morphine-related medicine (eg, oxycodone)


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you are unable to urinate or are having an asthma attack


• you have diarrhea due to antibiotic use or poisoning


• you are taking sodium oxybate (GHB), droxidopa, or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Max HC Liquid:

Some medical conditions may interact with Max HC Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat or other heart or blood vessel problems


• if you have a history of adrenal gland problems (eg, adrenal gland tumor); liver or kidney problems; high blood pressure; diabetes; stroke; glaucoma; increased pressure in the eye; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; trouble sleeping; an enlarged prostate or other prostate problems; or thyroid problems


• if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus


• if you have a history of head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures


• if you have a history of stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel, chronic constipation), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery


• if you are very ill or very weak or you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Max HC Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Max HC Liquid's side effects


• Barbiturates (eg, phenobarbital), cimetidine, digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased


• Naltrexone because it may decrease Max HC Liquid's effectiveness


• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Max HC Liquid


• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Max HC Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Max HC Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Max HC Liquid:

Use Max HC Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Max HC Liquid by mouth with or without food.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Max HC Liquid and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Max HC Liquid.

Important safety information:

• Max HC Liquid may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Max HC Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Max HC Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Do not use Max HC Liquid for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.


• Do not take diet or appetite control medicines while you are taking Max HC Liquid without checking with your doctor.


• Max HC Liquid has phenylephrine in it. Before you start any new medicine, check the label to see if it has phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.


• Max HC Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Max HC Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Max HC Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Max HC Liquid for a few days before the tests.


• Tell your doctor or dentist that you take Max HC Liquid before you receive any medical or dental care, emergency care, or surgery.


• Use Max HC Liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness or excitability.


• Caution is advised when using Max HC Liquid in CHILDREN; they may be more sensitive to its effects, especially drowsiness or excitability.


• Max HC Liquid should not be used in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Max HC Liquid may cause harm to the fetus if taken during late pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Max HC Liquid while you are pregnant. It is not known if Max HC Liquid is found in breast milk. Do not breast-feed while taking Max HC Liquid.

When used for long periods of time or at high doses, Max HC Liquid may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Max HC Liquid stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Max HC Liquid. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Max HC Liquid, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Max HC Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth; excitability; headache; loss of appetite; nausea; nervousness or anxiety; restlessness; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Max HC side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold, clammy skin; confusion; difficulty breathing; dilated pupils; flushing; hallucinations; loss of coordination; overexcitement; seizures; severe dizziness, lightheadedness, headache, or vomiting; severe drowsiness; unusually fast, slow, or irregular heartbeat.

Proper storage of Max HC Liquid:

Store Max HC Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Max HC Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Max HC Liquid, please talk with your doctor, pharmacist, or other health care provider.


• Max HC Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Max HC Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Max HC resources

• Max HC Side Effects (in more detail)
• Max HC Use in Pregnancy & Breastfeeding
• Max HC Drug Interactions
• Max HC Support Group
• 0 Reviews for Max HC - Add your own review/rating

Compare Max HC with other medications

• Cough and Nasal Congestion

Pseudoephedrine/Triprolidine

Pronunciation: soo-doe-e-FED-rin/try-PRO-li-deen
Generic Name: Pseudoephedrine/Triprolidine
Brand Name: Examples include Actifed and Sudafed Sinus Nighttime

Pseudoephedrine/Triprolidine is used for:

Temporarily relieving symptoms of hay fever, allergies, or the common cold, including nasal congestion, runny nose, sneezing, itching of the nose and throat, and itchy/watery eyes. It may also be used for other conditions as determined by your doctor.

Pseudoephedrine/Triprolidine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Pseudoephedrine/Triprolidine if:

• you are allergic to any ingredient in Pseudoephedrine/Triprolidine


• you are taking droxidopa or sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days


• you have severe high blood pressure or severe heart disease (eg, coronary artery disease, ischemic heart disease)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pseudoephedrine/Triprolidine:

Some medical conditions may interact with Pseudoephedrine/Triprolidine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have glaucoma or increased pressure in the eyes; high blood pressure; diabetes; heart or blood vessel disease; overactive thyroid; seizures; blockage of the stomach, bowel, or bladder; trouble breathing when you sleep; trouble sleeping; a breathing problem (eg, asthma, emphysema, chronic bronchitis); the blood disease porphyria; or an enlarged prostate or prostate disease; or if you have difficulty urinating

Some MEDICINES MAY INTERACT with Pseudoephedrine/Triprolidine. Tell your health care provider if you are taking any other medicines, especially if any of the following apply to you:

• Furazolidone or MAO inhibitors (eg, phenelzine) because side effects such as severe headache, high blood pressure, or high fever may occur


• Bromocriptine or sodium oxybate ( GHB) because the risk of side effects or toxic effects may be increased by Pseudoephedrine/Triprolidine


• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Pseudoephedrine/Triprolidine.


• Droxidopa because side effects such as irregular heartbeat or heart attack may occur


• Urinary alkalinizers (eg, sodium bicarbonate) because the side effects of Pseudoephedrine/Triprolidine may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pseudoephedrine/Triprolidine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pseudoephedrine/Triprolidine:

Use Pseudoephedrine/Triprolidine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Pseudoephedrine/Triprolidine may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• If you miss a dose of Pseudoephedrine/Triprolidine and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pseudoephedrine/Triprolidine.

Important safety information:

• Pseudoephedrine/Triprolidine may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Pseudoephedrine/Triprolidine. Using Pseudoephedrine/Triprolidine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Pseudoephedrine/Triprolidine. Pseudoephedrine/Triprolidine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.


• Contact your health care provider if symptoms last for more than 7 days or are accompanied by a fever.


• Diabetes patients - Pseudoephedrine/Triprolidine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.


• Pseudoephedrine/Triprolidine contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, including medicine used on the skin, read the ingredients to see if it also contains pseudoephedrine. If it does, or if you are uncertain if it does, contact your doctor or pharmacist.


• Do not take diet or appetite control medicines while you are taking Pseudoephedrine/Triprolidine without checking with your doctor.


• Do not exceed the recommended dose or take Pseudoephedrine/Triprolidine for longer than prescribed without checking with your doctor.


• If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Pseudoephedrine/Triprolidine.


• Use Pseudoephedrine/Triprolidine with caution in the ELDERLY because they may be more sensitive to its effects.


• Pseudoephedrine/Triprolidine is not recommended for use in CHILDREN younger than 6 years of age without first checking with your doctor.


• Caution is advised when using Pseudoephedrine/Triprolidine in CHILDREN because they may be more sensitive to its effects, especially excitability.


• PREGNANCY AND BREAST-FEEDING: If you become pregnant while taking Pseudoephedrine/Triprolidine, discuss with your doctor the benefits and risks of using Pseudoephedrine/Triprolidine during pregnancy. If you are or will be breast-feeding while you are using Pseudoephedrine/Triprolidine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Pseudoephedrine/Triprolidine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability (especially in children); headache; loss of appetite; nausea; nervousness; restlessness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased coordination; difficulty urinating; fast or irregular heartbeat; fever; hallucinations; seizure; severe dizziness and drowsiness; severe nervousness, anxiety, or restlessness; tremors; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Pseudoephedrine/Triprolidine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish-colored skin; difficulty breathing; dilated pupils; fast or irregular heartbeat; fever; flushing; hallucinations; mental or mood changes; seizures; severe drowsiness or dizziness; severe excitability; severe nausea or vomiting; sweating; tremors.

Proper storage of Pseudoephedrine/Triprolidine:

Store Pseudoephedrine/Triprolidine at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pseudoephedrine/Triprolidine out of the reach of children and away from pets.

General information:

• If you have any questions about Pseudoephedrine/Triprolidine, please talk with your doctor, pharmacist, or other health care provider.


• Pseudoephedrine/Triprolidine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Pseudoephedrine/Triprolidine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Pseudoephedrine/Triprolidine resources

• Pseudoephedrine/Triprolidine Side Effects (in more detail)
• Pseudoephedrine/Triprolidine Use in Pregnancy & Breastfeeding
• Drug Images
• Pseudoephedrine/Triprolidine Drug Interactions
• Pseudoephedrine/Triprolidine Support Group
• 8 Reviews for Pseudoephedrine/Triprolidine - Add your own review/rating

Compare Pseudoephedrine/Triprolidine with other medications

• Cold Symptoms
• Hay Fever

milnacipran

mil-NA-si-pran

Oral route(Tablet)

Milnacipran hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) similar to antidepressants and drugs to treat other psychiatric disorders. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Milnacipran hydrochloride is not approved for treatment of MDD or for use in pediatric patients .

Commonly used brand name(s)

In the U.S.

• Savella

Available Dosage Forms:

• Tablet

Pharmacologic Class: Serotonin/Norepinephrine Reuptake Inhibitor

Uses For milnacipran

Milnacipran is used to treat a condition called fibromyalgia, which causes muscle pain and stiffness.

Milnacipran belongs to a group of medicines known as selective serotonin and norepinephrine reuptake inhibitors (SNRIs). These medicines work by increasing the activity of certain chemicals in the brain called serotonin and norepinephrine.

milnacipran is available only with your doctor's prescription.

Before Using milnacipran

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For milnacipran, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to milnacipran or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of milnacipran in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of milnacipran in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving milnacipran.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking milnacipran, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using milnacipran with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Brofaromine


• Clorgyline


• Furazolidone


• Iproniazid


• Isocarboxazid


• Lazabemide


• Linezolid


• Moclobemide


• Nialamide


• Pargyline


• Phenelzine


• Procarbazine


• Rasagiline


• Selegiline


• Toloxatone


• Tranylcypromine

Using milnacipran with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abciximab


• Acenocoumarol


• Almotriptan


• Amisulpride


• Anagrelide


• Ancrod


• Anisindione


• Antithrombin III Human


• Aripiprazole


• Aspirin


• Avitriptan


• Benperidol


• Bivalirudin


• Chlorpromazine


• Cilostazol


• Citalopram


• Clopidogrel


• Clovoxamine


• Clozapine


• Danaparoid


• Defibrotide


• Dermatan Sulfate


• Desirudin


• Desvenlafaxine


• Dextromethorphan


• Dicumarol


• Dipyridamole


• Duloxetine


• Eletriptan


• Epoprostenol


• Eptifibatide


• Escitalopram


• Femoxetine


• Fluoxetine


• Fluphenazine


• Fluvoxamine


• Fondaparinux


• Frovatriptan


• Haloperidol


• Heparin


• Iloprost


• Lamifiban


• Lexipafant


• Lithium


• Loxapine


• Mesoridazine


• Metoclopramide


• Molindone


• Naratriptan


• Nefazodone


• Olanzapine


• Paroxetine


• Pentosan Polysulfate Sodium


• Perphenazine


• Phenindione


• Phenprocoumon


• Pimozide


• Promazine


• Quetiapine


• Risperidone


• Rizatriptan


• Sertraline


• Sibrafiban


• Sibutramine


• Sulfinpyrazone


• Sulodexide


• Sumatriptan


• Tapentadol


• Thioridazine


• Thiothixene


• Ticlopidine


• Tirofiban


• Tramadol


• Trifluoperazine


• Tryptophan


• Venlafaxine


• Vilazodone


• Warfarin


• Xemilofiban


• Zimeldine


• Ziprasidone


• Zolmitriptan

Using milnacipran with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aceclofenac


• Acemetacin


• Alclofenac


• Benoxaprofen


• Bromfenac


• Bufexamac


• Carprofen


• Celecoxib


• Clonixin


• Dexketoprofen


• Diclofenac


• Diflunisal


• Dipyrone


• Droxicam


• Etodolac


• Etofenamate


• Etoricoxib


• Felbinac


• Fenbufen


• Fenoprofen


• Fentiazac


• Floctafenine


• Flufenamic Acid


• Flurbiprofen


• Ibuprofen


• Indomethacin


• Indoprofen


• Isoxicam


• Ketoprofen


• Ketorolac


• Lornoxicam


• Meclofenamate


• Mefenamic Acid


• Meloxicam


• Morniflumate


• Nabumetone


• Naproxen


• Niflumic Acid


• Nimesulide


• Oxaprozin


• Parecoxib


• Phenylbutazone


• Pirazolac


• Piroxicam


• Pirprofen


• Propyphenazone


• Proquazone


• Rofecoxib


• Sulindac


• Suprofen


• Tenidap


• Tenoxicam


• Tiaprofenic Acid


• Tolmetin


• Valdecoxib


• Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using milnacipran with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use milnacipran, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of milnacipran. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems or


• Depression, history of or


• Enlarged prostate or


• Heart disease or


• Heart rhythm problems or


• Hypertension (high blood pressure) or


• Hyponatremia (low sodium in the blood) or


• Liver disease or


• Mania, history of or


• Narrow-angle glaucoma, controlled or


• Painful or difficult urination, history of or


• Seizures, history of or


• Urinary tract blockage—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

• Narrow-angle glaucoma, uncontrolled—Should not be used in patients with this condition.

• Tartrazine (a dye) sensitivity, history of—milnacipran contains tartrazine, which may cause an allergic reaction in some patients.

Proper Use of milnacipran

Take milnacipran only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

milnacipran should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take milnacipran with or without food.

Dosing

The dose of milnacipran will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of milnacipran. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For treatment of fibromyalgia:
    
    • Adults—
      
      • Day 1: 12.5 milligram (mg) once.
      
      
      • Days 2 to 3: 25 mg per day (12.5 mg two times a day).
      
      
      • Days 4 to 7: 50 mg per day (25 mg two times a day).
      
      
      • After day 7: 100 mg per day (50 mg two times a day).
      
      
      • Your doctor may increase your dose up to 200 mg per day (100 mg two times a day).
      
      
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of milnacipran, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using milnacipran

It is important that your doctor check your progress at regular visits to allow for changes in your dose and to help reduce any side effects.

It is important to tell your doctor if you become pregnant. Your doctor may want you to join a pregnancy registry for patients taking milnacipran.

Milnacipran may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.

Do not take milnacipran during the 2 weeks (14 days) after stopping a monoamine oxidase inhibitor (MAOI) (e.g., isocarboxazid [Marplan®], phenelzine [Nardil®], selegiline [Eldepryl®], or tranylcypromine [Parnate®]). Do not take an MAO inhibitor for at least 5 days after stopping milnacipran. If you do, you may have serious side effects such as seizures. Talk to your doctor about this if you have questions.

Make sure your doctor knows if you are also using aspirin, NSAIDs (e.g., ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, or Motrin®), or a blood thinner (e.g., warfarin or Coumadin®). Milnacipran may increase your risk of bleeding problems when taken together with these medicines.

Make sure your doctor knows about all the other medicines you are using. milnacipran may cause a serious condition called serotonin syndrome or neuroleptic malignant syndrome (NMS)-like reactions when taken with certain medicines such as lithium, tryptophan, or some pain or migraine medicines (e.g., rizatriptan [Maxalt®], sumatriptan [Imitrex®], tramadol [Ultram®], or zolmitriptan [Zomig®]. Check with your doctor first before taking any other medicines.

You will also need to have your blood pressure and pulse measured before starting and while you are using milnacipran. If you notice any change to your recommended blood pressure or pulse rate, call your doctor right away. If you have questions about this, talk to your doctor.

Liver problems may occur while you are using milnacipran. Stop using milnacipran and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.

Avoid taking alcohol while you are using milnacipran.

milnacipran may cause some people to become less alert than they are normally. Make sure you know how you react to milnacipran before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Do not suddenly stop taking milnacipran without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely to decrease the chance of side effects.

milnacipran Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Blurred vision


• body aches or pain


• chills


• cough


• difficulty with breathing


• dizziness


• ear congestion


• fast, irregular, pounding, or racing heartbeat or pulse


• fear or nervousness


• fever


• headache


• increased sweating


• loss of voice


• nasal congestion


• pounding in the ears


• runny nose


• slow or fast heartbeat


• sneezing


• sore throat


• unusual tiredness or weakness

Less common

• Back pain


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• chest discomfort


• chest pain


• chills


• decrease in frequency of urination


• decrease in urine volume


• difficult or painful urination


• difficulty in passing urine (dribbling)


• frequent urination


• groin pain


• muscle aches


• pain or burning with urination


• shakiness in the legs, arms, hands, or feet


• shortness of breath


• swollen, tender prostate


• tightness in the chest


• wheezing

Rare

• Bladder pain


• bloating or swelling of the face, arms, hands, lower legs, or feet


• bloody or cloudy urine


• bruise


• discouragement


• fall


• feeling sad or empty


• frequent urge to urinate


• full or bloated feeling


• heartburn


• increased or decreased weight


• irritability


• lack of appetite


• loss of interest or pleasure


• lower back or side pain


• pressure in the stomach


• rapid weight gain


• swelling of the abdominal or stomach area


• tingling of the hands or feet


• tiredness


• trouble concentrating


• trouble sleeping


• unusual weight gain or loss


• vomiting

Incidence not known

• Agitation


• black, tarry stools


• bleeding gums


• blistering, peeling, or loosening of the skin


• blood in the urine or stools


• coma


• confusion as to time, place, or person


• convulsions


• dark-colored urine


• decreased urine output


• diarrhea


• difficulty with swallowing


• general tiredness and weakness


• high fever


• holding false beliefs that cannot be changed by fact


• increased sweating


• increased thirst


• itching


• joint or muscle pain


• light-colored stools


• loss of balance control


• loss of consciousness


• mask-like face


• muscle cramps or spasms


• muscle pain or stiffness


• overactive reflexes


• pinpoint red spots on the skin


• poor coordination


• red irritated eyes


• red skin lesions, often with a purple center


• restlessness


• seeing, hearing, or feeling things that are not there


• seizures


• severe muscle stiffness


• shuffling walk


• slowed movements


• slurred speech


• sores, ulcers, or white spots on the lips or in the mouth


• stiffness of the arms and legs


• sweating


• swelling of the face, ankles, fingers, or lower legs


• swollen glands


• talking or acting with excitement you cannot control


• tic-like (jerky) movements of the head, face, mouth, and neck


• tiredness


• trembling and shaking of the fingers and hands


• twitching


• unusual bleeding or bruising


• unusual excitement, nervousness, or restlessness


• unusually pale skin


• upper right abdominal pain


• weight gain


• yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Feeling of warmth


• headache, severe and throbbing


• redness of the face, neck, arms, and occasionally, upper chest


• sleeplessness


• sudden sweating


• unable to sleep

Less common

• Abdominal or stomach pain


• change or problem with discharge of semen


• decreased appetite


• decreased interest in sexual intercourse


• inability to have or keep an erection


• loss in sexual ability, desire, drive, or performance


• not able to ejaculate semen


• rash


• swelling of the testes

Rare

• Acid or sour stomach


• belching


• bloated


• change in taste


• excess air or gas in the stomach or intestines


• full feeling


• heartburn


• indigestion


• irritability


• loss of taste


• night sweats


• passing gas


• sleepiness or unusual drowsiness


• stomach discomfort, upset, or pain

Incidence not known

• Swelling of the breasts or unusual milk production


• unexpected or excess milk flow from the breasts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: milnacipran side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More milnacipran resources

• Milnacipran Side Effects (in more detail)
• Milnacipran Dosage
• Milnacipran Use in Pregnancy & Breastfeeding
• Milnacipran Drug Interactions
• Milnacipran Support Group
• 206 Reviews for Milnacipran - Add your own review/rating

• Milnacipran MedFacts Consumer Leaflet (Wolters Kluwer)


• Savella Prescribing Information (FDA)


• Savella Consumer Overview

Compare milnacipran with other medications

• Fibromyalgia
• Reflex Sympathetic Dystrophy Syndrome

Chlorpheniramine Sustained-Release Capsules

Pronunciation: klor-fen-IHR-ah-meen
Generic Name: Chlorpheniramine
Brand Name: QDALL AR

Chlorpheniramine Sustained-Release Capsules are used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg, colds), allergies, and hay fever. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine Sustained-Release Capsules are an antihistamine. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing.

Do NOT use Chlorpheniramine Sustained-Release Capsules if:

• you are allergic to any ingredient in Chlorpheniramine Sustained-Release Capsules


• you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Chlorpheniramine Sustained-Release Capsules:

Some medical conditions may interact with Chlorpheniramine Sustained-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma, lung problems (eg, emphysema), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Chlorpheniramine Sustained-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Furazolidone, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Chlorpheniramine Sustained-Release Capsules may be increased


• Hydantoins (eg, phenytoin) because side effects may be increased by Chlorpheniramine Sustained-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine Sustained-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Chlorpheniramine Sustained-Release Capsules:

Use Chlorpheniramine Sustained-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Chlorpheniramine Sustained-Release Capsules may be taken with or without food.


• Swallow Chlorpheniramine Sustained-Release Capsules whole. Do not break, crush, or chew before swallowing.


• If you miss a dose of Chlorpheniramine Sustained-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine Sustained-Release Capsules.

Important safety information:

• Chlorpheniramine Sustained-Release Capsules may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Chlorpheniramine Sustained-Release Capsules. Using Chlorpheniramine Sustained-Release Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Do NOT exceed the recommended dose or take Chlorpheniramine Sustained-Release Capsules for longer than prescribed without checking with your doctor.


• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.


• Chlorpheniramine Sustained-Release Capsules may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine Sustained-Release Capsules. Use a sunscreen or protective clothing if you must be outside for a prolonged period.


• If you are scheduled for allergy skin testing, do not take Chlorpheniramine Sustained-Release Capsules for several days before the test because it may decrease your response to the skin tests.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Chlorpheniramine Sustained-Release Capsules.


• Use Chlorpheniramine Sustained-Release Capsules with caution in the ELDERLY because they may be more sensitive to its effects.


• Caution is advised when using Chlorpheniramine Sustained-Release Capsules in CHILDREN because they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Chlorpheniramine Sustained-Release Capsules, discuss with your doctor the benefits and risks of using Chlorpheniramine Sustained-Release Capsules during pregnancy. It is unknown if Chlorpheniramine Sustained-Release Capsules are excreted in breast milk. Do not breast-feed while taking Chlorpheniramine Sustained-Release Capsules.

Possible side effects of Chlorpheniramine Sustained-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Chlorpheniramine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Chlorpheniramine Sustained-Release Capsules:

Store Chlorpheniramine Sustained-Release Capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine Sustained-Release Capsules out of the reach of children and away from pets.

General information:

• If you have any questions about Chlorpheniramine Sustained-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.


• Chlorpheniramine Sustained-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine Sustained-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorpheniramine resources

• Chlorpheniramine Side Effects (in more detail)
• Chlorpheniramine Use in Pregnancy & Breastfeeding
• Drug Images
• Chlorpheniramine Drug Interactions
• Chlorpheniramine Support Group
• 18 Reviews for Chlorpheniramine - Add your own review/rating

Compare Chlorpheniramine with other medications

• Allergic Reactions
• Cold Symptoms
• Hay Fever
• Urticaria

Venlafaxine Extended-Release Tablets

Pronunciation: VEN-la-FAX-een
Generic Name: Venlafaxine
Brand Name: Effexor XR

Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using Venlafaxine Extended-Release Tablets outweigh the risks.

Families and caregivers must closely watch patients who take Venlafaxine Extended-Release Tablets. It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor.

Venlafaxine Extended-Release Tablets are used for:

Treating depression, generalized or social anxiety disorder, or panic disorder. It may also be used for other conditions as determined by your doctor.

Venlafaxine Extended-Release Tablets are a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by restoring the balance of certain natural substances in the brain (serotonin and norepinephrine), which helps to improve certain mood problems.

Do NOT use Venlafaxine Extended-Release Tablets if:

• you are allergic to any ingredient in Venlafaxine Extended-Release Tablets


• you are taking or have taken linezolid, methylene blue, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days


• you are taking a fenfluramine derivative (eg, dexfenfluramine), nefazodone, sibutramine, tramadol, or tryptophan

Contact your doctor or health care provider right away if any of these apply to you.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Venlafaxine Extended-Release Tablets:

Some medical conditions may interact with Venlafaxine Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse


• if you have a history of seizures, heart problems (eg, heart failure, irregular heartbeat), abnormal electrocardiograms (ECGs), a recent heart attack, high blood pressure, high cholesterol, an overactive thyroid, liver problems, lung problems, kidney problems, stomach or bowel bleeding, blood or bleeding problems, increased eye pressure (eg, glaucoma), nervous system problems, or metabolism problems


• if you are dehydrated, have low blood sodium levels, or drink alcohol


• if you will be having electroconvulsive therapy (ECT)

Some MEDICINES MAY INTERACT with Venlafaxine Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Certain diet medicines (eg, phentermine, fenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), methylene blue, metoclopramide, nefazodone, rasagiline, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, duloxetine), St. John's wort, tramadol , trazodone, tricyclic antidepressants (eg, amitriptyline), or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur


• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased


• Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood sodium levels may be increased


• Azole antifungals (eg, ketoconazole) or cimetidine because they may increase the risk of Venlafaxine Extended-Release Tablets's side effects


• Cyproheptadine because it may decrease Venlafaxine Extended-Release Tablets's effectiveness


• Aripiprazole, clozapine, haloperidol, phenothiazines (eg, chlorpromazine, thioridazine), or risperidone because the risk of their side effects may be increased by Venlafaxine Extended-Release Tablets


• Metoprolol because its effectiveness may be decreased by Venlafaxine Extended-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Venlafaxine Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Venlafaxine Extended-Release Tablets:

Use Venlafaxine Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Venlafaxine Extended-Release Tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Venlafaxine Extended-Release Tablets refilled.


• Take Venlafaxine Extended-Release Tablets by mouth with food.


• Take Venlafaxine Extended-Release Tablets with a full glass of water (8 oz/240 mL).


• Swallow Venlafaxine Extended-Release Tablets whole. Do not break, crush, chew, or place in water before swallowing.


• Venlafaxine Extended-Release Tablets works best if it is taken at the same time each day.


• Continue to take Venlafaxine Extended-Release Tablets even if you feel well. Do not miss any doses.


• Do not suddenly stop taking Venlafaxine Extended-Release Tablets without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, drowsiness, confusion, headache, increased sweating, loss of coordination or balance, flu-like symptoms, nausea, ringing in the ears, seizures, tremor, trouble sleeping, or unusual tiredness. You will be closely monitored when you start Venlafaxine Extended-Release Tablets and whenever a change in dose is made.


• If you miss a dose of Venlafaxine Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Venlafaxine Extended-Release Tablets.

Important safety information:

• Venlafaxine Extended-Release Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Venlafaxine Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Venlafaxine Extended-Release Tablets without checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Children, teenagers, and young adults who take Venlafaxine Extended-Release Tablets may be at increased risk for suicidal thoughts or actions. Watch all patients who take Venlafaxine Extended-Release Tablets closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.


• Serotonin syndrome is a possibly fatal syndrome that can be caused by Venlafaxine Extended-Release Tablets. Your risk may be greater if you take Venlafaxine Extended-Release Tablets with certain other medicines (eg, "triptans," MAOIs, SSRIs). Symptoms may include agitation; coma; confusion; excessive sweating; fever; fast or irregular heartbeat; hallucinations; nausea, vomiting, or diarrhea; and tremor. Contact your doctor at once if you have any of these symptoms.


• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Venlafaxine Extended-Release Tablets. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.


• If your doctor tells you to stop taking Venlafaxine Extended-Release Tablets, you will need to wait for a period of time before beginning to take certain other medicines (eg, MAOIs, nefazodone, thioridazine). Ask your doctor when you should start to take your new medicines after you have stopped taking Venlafaxine Extended-Release Tablets.


• Venlafaxine Extended-Release Tablets may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.


• Lab tests, including blood pressure and blood cholesterol levels, may be performed while you use Venlafaxine Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Venlafaxine Extended-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially low blood sodium levels.


• Caution is advised when using Venlafaxine Extended-Release Tablets in CHILDREN; they may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.


• Venlafaxine Extended-Release Tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• Venlafaxine Extended-Release Tablets may cause weight changes and growth changes. CHILDREN and teenagers may need regular weight and growth checks while they take Venlafaxine Extended-Release Tablets.


• PREGNANCY and BREAST-FEEDING: Venlafaxine Extended-Release Tablets may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Venlafaxine Extended-Release Tablets while you are pregnant. Venlafaxine Extended-Release Tablets are found in breast milk. Do not breast-feed while taking Venlafaxine Extended-Release Tablets.

Possible side effects of Venlafaxine Extended-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal dreams; blurred vision; changes in taste; constipation; decreased sexual desire or ability; dizziness; drowsiness; dry mouth; flushing; headache; increased sweating; loss of appetite; nausea; nervousness; stomach upset; trouble sleeping; vomiting; weakness; weight loss; yawning.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; blood in the stool; chest pain or discomfort; confusion; decreased concentration; decreased coordination; decreased urination; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; memory problems; new or worsening aggressiveness, agitation, anxiety, hostility, impulsiveness, inability to sit still, irritability, panic attacks, or restlessness; persistent or severe ringing in the ears; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety, nervousness, or trouble sleeping; severe or persistent cough; severe or persistent headache, dizziness, stomach pain, or weakness; shortness of breath; significant weight loss; suicidal thoughts or attempts; tremor; trouble concentrating; unsteadiness or loss of coordination; unusual bruising or bleeding; unusual or severe mental or mood changes; unusual weakness; vision problems; worsening of depression.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Venlafaxine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; dilated pupils; fainting; fast, slow, or irregular heartbeat; muscle pain or weakness; new or worsening mental or mood problems; seizures; severe or persistent dizziness, drowsiness, or vomiting; trouble breathing; yellowing of the eyes or skin.

Proper storage of Venlafaxine Extended-Release Tablets:

Store Venlafaxine Extended-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Venlafaxine Extended-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Venlafaxine Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Venlafaxine Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Venlafaxine Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Venlafaxine resources

• Venlafaxine Side Effects (in more detail)
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• Venlafaxine Use in Pregnancy & Breastfeeding
• Drug Images
• Venlafaxine Drug Interactions
• Venlafaxine Support Group
• 338 Reviews for Venlafaxine - Add your own review/rating

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Elixophyllin-GG

Generic Name: guaifenesin and theophylline (gwye FEN e sin and thee OFF il in)

Brand Names: Ed-Bron G, Elixophyllin-GG

What is Elixophyllin-GG (guaifenesin and theophylline)?

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Theophylline is a bronchodilator. Theophylline works in several ways: It relaxes muscles in your lungs and chest to increase airflow, decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and increases the contractions of your diaphragm so that more air is drawn into the lungs.

The combination of guaifenesin and theophylline is used to treat symptoms of asthma, bronchitis, and emphysema.

Guaifenesin and theophylline may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Elixophyllin-GG (guaifenesin and theophylline)?

Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, an increased heart rate, or a headache. These symptoms could be signs of too much theophylline in your blood.

Do not start or stop smoking without first talking to your doctor. Smoking changes the way your body uses theophylline, and you may need a dose adjustment.

Do not take more of this medicine than is prescribed without consulting your doctor. Seek medical attention if you are having increasingly difficult breathing.

What should I discuss with my healthcare provider before taking Elixophyllin-GG (guaifenesin and theophylline)?

You should not take this medication if you are allergic to guaifenesin or theophylline, or if you have:

• 
  

  a stomach ulcer; or

  
  


• 
  

  epilepsy or another seizure disorder.

  
  

Before taking guaifenesin and theophylline, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  heart disease or high blood pressure;

  
  


• 
  

  a heart rhythm disorder;

  
  


• 
  

  congestive heart failure;

  
  


• 
  

  fluid in your lungs;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  fever;

  
  


• 
  

  liver disease; or

  
  


• 
  

  kidney disease.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Guaifenesin and theophylline can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

How should I take Elixophyllin-GG (guaifenesin and theophylline)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with a full glass of water. Drink plenty of fluids to help loosen congestion and thin mucus. Guaifenesin and theophylline can be taken with food to lessen stomach upset.

Take your doses at the same time every day to keep a constant level of guaifenesin and theophylline in your blood.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not switch brands or formulation (capsule, liquid) without your doctor's approval.

Store guaifenesin and theophylline at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, headache, sleep problems, tremors, irritability, restlessness, fast heart rate, or seizure (convulsions).

What should I avoid while taking Elixophyllin-GG (guaifenesin and theophylline)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol while taking guaifenesin and theophylline. Alcohol can increase some of the side effects of this medication. Do not start or stop smoking without first talking to your doctor. Smoking changes the way your body uses theophylline, and you may need a dose adjustment.

Avoid eating grilled or char-broiled foods. These foods may affect how theophylline works. Talk to your doctor before making changes in your diet.

Avoid caffeine (such as in coffee, tea, or cola), which can increase the side effects of theophylline.

Elixophyllin-GG (guaifenesin and theophylline) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  seizure (convulsions);

  
  


• 
  

  fast or uneven heart rate; or

  
  


• 
  

  severe nausea or vomiting.

  
  

Less serious side effects may include:

• 
  

  mild skin rash;

  
  


• 
  

  slight nausea, decreased appetite, or weight loss;

  
  


• 
  

  restlessness, tremor, or insomnia; or

  
  


• 
  

  headache, lightheadedness, or dizziness.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Elixophyllin-GG (guaifenesin and theophylline)?

Many drugs can interact with guaifenesin and theophylline. Below is just a partial list. Tell your doctor if you are using:

• 
  

  birth control pills;

  
  


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  ketoconazole (Nizoral);

  
  


• 
  

  an antibiotic such as ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (Ery-Tab, E.E.S, E-Mycin, others), levofloxacin (Levaquin), or rifampin (Rifadin, Rifamate, Rimactane);

  
  


• 
  

  a thyroid hormone such as levothyroxine (Synthroid, Levoxyl, Levothroid, others);

  
  


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  an interferon product such as Intron A, Alferon N, Infergen, Roferon-A, Betaseron, Avonex, Actimmune, and others;

  
  


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  a calcium channel blocker such as diltiazem (Cardizem, Dilacor XR, Tiazac), nifedipine (Procardia, Adalat), verapamil (Verelan, Calan, Isoptin), and others;

  
  


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  a beta-blocker such as atenolol (Tenormin), metoprolol (Lopressor, Toprol), propranolol (Inderal), timolol (Blocadren), and others;

  
  


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  asthma medication such as albuterol (Ventolin, Proventil, Volmax, others), salmeterol (Serevent), and others;

  
  


• 
  

  a diuretic (water pill); or

  
  


• 
  

  seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).

  
  

There are many other medicines that can interact with guaifenesin and theophylline. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

More Elixophyllin-GG resources

• Elixophyllin-GG Side Effects (in more detail)
• Elixophyllin-GG Use in Pregnancy & Breastfeeding
• Elixophyllin-GG Drug Interactions
• 0 Reviews for Elixophyllin-GG - Add your own review/rating

• Ed-Bron G Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Quibron MedFacts Consumer Leaflet (Wolters Kluwer)

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Where can I get more information?

• Your pharmacist can provide more information about guaifenesin and theophylline.

See also: Elixophyllin-GG side effects (in more detail)

Eneset 2 oral and rectal

Generic Name: barium sulfate (oral and rectal) (BER ee um SUL fate)

Brand Names: Anatrast, Bar-Test, Baricon, Baro-Cat, Barosperse, Bear-E-Yum GI, CheeTah, CheeTah Butterscotch, CheeTah Chocolaty-Fudge, CheeTah Orange, CheeTah Raspberry, Digibar 190, E-Z AC, E-Z Disk, E-Z Dose Kit with Polibar Plus, E-Z Paste, E-Z-Cat, E-Z-Cat Dry, E-Z-HD, E-Z-Paque, Enecat, Eneset 2, Enhancer, Entero VU, Entero-H, Entrobar, Esopho-Cat, Intropaste, Liqui-Coat HD, Liquid Barosperse, Liquid E-Z Paque, Liquid Polibar, Liquid Polibar Plus, Maxibar, Medebar Plus, Medebar Super 250, Polibar ACB, Readi-Cat, Readi-Cat 2, Scan C, Sitzmarks, Smoothie Readi-Cat 2, Sol-O-Pake, Tagitol V, Tonojug, Tonopaque, Varibar Honey, Varibar Nectar, Varibar Pudding, Varibar Thin, Varibar Thin Honey, Volumen

What is barium sulfate?

Barium sulfate is in a group of drugs called contrast agents. Barium sulfate works by coating the inside of your esophagus, stomach, or intestines which allows them to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Barium sulfate is used to help diagnose certain disorders of the esophagus, stomach, or intestines.

Barium sulfate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about barium sulfate?

You should not use this medication if you are allergic to barium sulfate. Tell your doctor if you have ever had an allergic reaction to a contrast agent.

Before you use barium sulfate, tell your doctor if you have any allergies, or if you have asthma, cystic fibrosis, heart disease or high blood pressure, rectal cancer, a colostomy, a blockage in your stomach or intestines, a condition called pseudotumor cerebri, or if you have recently had a rectal biopsy or surgery on your esophagus, stomach, or intestines.

Tell your doctor if you are pregnant or breast-feeding before your medical test.

Carefully follow your doctor's instructions about what to eat or drink within the 24-hour period before your test.

Serious side effects of barium sulfate may include severe stomach pain, sweating, ringing in your ears, pale skin, weakness, or severe cramping, diarrhea, or constipation

What should I discuss with my health care provider before using barium sulfate?

You should not use barium sulfate if you are allergic to it. Tell your doctor if you have ever had an allergic reaction to a contrast agent.

To make sure you can safely use barium sulfate, tell your doctor if you have any of these other conditions:

• 
  

  asthma, eczema, or allergies;

  
  


• 
  

  a blockage in your stomach or intestines;

  
  


• 
  

  cystic fibrosis;

  
  


• 
  

  a colostomy;

  
  


• 
  

  rectal cancer;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  Hirschsprung's disease (a disorder of the intestines);

  
  


• 
  

  a condition called pseudotumor cerebri (high pressure inside the skull that may cause headaches, vision loss, or other symptoms);

  
  


• 
  

  a recent history of surgery on your esophagus, stomach, or intestines;

  
  


• 
  

  a history of perforation (a hole or tear) in your esophagus, stomach, or intestines;

  
  


• 
  

  if you have recently had a rectal biopsy;

  
  


• 
  

  if you have ever choked on food by accidentally inhaling it into your lungs;

  
  


• 
  

  if you are allergic to simethicone (Gas-X, Phazyme, and others); or

  
  


• 
  

  if you are allergic to latex rubber.

  
  

It is not known whether barium sulfate will harm an unborn baby, but the radiation used in x-rays and CT scans may be harmful. Before your medical test, tell your doctor if you are pregnant. Barium sulfate may pass into breast milk and could harm a nursing baby. Before your medical test, tell your doctor if you are breast-feeding a baby.

How should I use barium sulfate?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Barium sulfate comes in tablets, paste, cream, or liquid forms.

In some cases, barium sulfate is taken by mouth. The liquid form may also be used as a rectal enema.

You may need to begin using this medication at home a day before your medical test. Follow your doctor's instructions about how much of the medication to use and how often.

If you are receiving barium sulfate as a rectal enema, a healthcare professional will give you the medication at the clinic or hospital where your testing will take place.

Do not crush, chew, or break a barium sulfate tablet. Swallow the pill whole.

Dissolve the barium sulfate powder in a small amount of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

If you receive the medication as a liquid to take by mouth, shake the liquid well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Carefully follow your doctor's instructions about what to eat or drink within the 24-hour period before your test.

Store at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

If you are using barium sulfate at home, call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe stomach pain, ongoing diarrhea, confusion, or weakness.

What should I avoid before or after using barium sulfate?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Barium sulfate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  severe stomach pain;

  
  


• 
  

  severe cramping, diarrhea, or constipation;

  
  


• 
  

  sweating;

  
  


• 
  

  ringing in your ears;

  
  


• 
  

  confusion, fast heart rate; or

  
  


• 
  

  pale skin, weakness.

  
  

Less serious side effects may include:

• 
  

  mild stomach cramps;

  
  


• 
  

  nausea, vomiting;

  
  


• 
  

  loose stools or mild constipation.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect barium sulfate?

There may be other drugs that can interact with barium sulfate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Eneset 2 resources

• Eneset 2 Side Effects (in more detail)
• Eneset 2 Use in Pregnancy & Breastfeeding
• Eneset 2 Support Group
• 0 Reviews for Eneset 2 - Add your own review/rating

Compare Eneset 2 with other medications

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Where can I get more information?

• Your doctor or pharmacist can provide more information about barium sulfate.

See also: Eneset 2 side effects (in more detail)